Optical Rotation Analysis, Spectroscopy Services, and More
By Exeter Analytical (UK) Ltd in Coventry
At Exeter Analytical (UK) Ltd in Coventry, we pride ourselves on delivering precise and reliable elemental analysis services backed by UKAS ISO 17025 accreditation, ensuring the highest quality and reliability. Our comprehensive range of analytical techniques meets the diverse needs of industries including pharmaceuticals, environmental monitoring, and materials science. Find out more about industry applications and our projects or get in touch to speak to our team.
1994
EST.
CALL OUR TEAM ON 024 7632 3223 FOR A QUOTE
Optical Rotation Analysis Services
Unlock the secrets of molecular structure and purity with Optical Rotation Analysis services. We provide highly accurate and reliable measurements crucial for diverse applications, from new compound characterization to stringent pharmaceutical quality control.
Precision and Versatility in Polarimetry
​Our state-of-the-art polarimeter boasts an exceptional accuracy of ±0.0020, ensuring the integrity of your data. We offer comprehensive optical rotation measurements across five critical wavelengths: 589nm, 578nm, 546nm, 436nm, and 365nm. This multi-wavelength capability provides deeper insights into your samples' optical properties.
For optimal consistency and reproducibility, our polarimeter cell features integrated temperature control, typically maintained at 25°C. This precise temperature regulation is vital for accurate specific rotation determination.
Key Applications of Optical Rotation
Our optical rotation services are indispensable for:
Characterization of Newly Synthesised Compounds: Confirm the enantiomeric purity and structural integrity of your novel chemical entities.
Quality Control of Pharmaceutical Substances: Ensure the enantiomeric purity of active pharmaceutical ingredients (APIs) and other drug components, critical for efficacy and safety.
Enantiomeric Purity Determination: Accurately assess the ratio of enantiomers in a sample, a key parameter in many chemical and pharmaceutical processes.
Sample Submission Requirements
To ensure the most efficient and accurate analysis, please provide:
Sample Requirements: Typically, 2-30mg per analysis.
Other Requirements: Please specify the desired concentration, solvent, and temperature for your analysis.
Contact us today to discuss your optical rotation analysis needs and discover how our advanced polarimetry services can support your research and quality control objectives.
Nuclear Magnetic Resonance (NMR) Spectroscopy Services
Unravel the intricate structures of organic molecules with Nuclear Magnetic Resonance (NMR) Spectroscopy services. As a cornerstone technique in chemical analysis, NMR provides unparalleled insights into molecular architecture, making it indispensable for structural clarification and compound identification.
Understanding NMR Spectroscopy
NMR spectroscopy operates by placing molecules within a powerful magnetic field, inducing distinct energy states. These states are then detected through the absorption of electromagnetic radiation in the radio frequency region. The resulting NMR spectrum offers highly specific and detailed structural information, allowing for precise identification and characterization of your compounds.
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​NMR spectroscopy services utilise a high-performance 400 MHz NMR instrument, capable of producing multinuclear spectra. This versatility allows us to analyse a wide range of nuclei, including but not limited to 1H and 13C, providing comprehensive structural data.
Key Applications of NMR Spectroscopy
Our NMR analysis is crucial for:
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Organic Molecule Structure Elucidation: Determine the complete chemical structure of unknown or newly synthesized organic compounds.
Compound Identification and Verification: Confirm the identity and purity of synthesized compounds, crucial for research and development.
Reaction Monitoring: Track the progress of chemical reactions and identify intermediates or byproducts.
Mixture Analysis: Quantify components in complex mixtures without the need for prior separation.
Conformational Analysis: Gain insights into the three-dimensional arrangement of atoms in a molecule.
Sample Submission Requirements
To ensure the most effective and accurate NMR analysis, please provide:
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Sample Requirements:
Minimum 50 mg for 13C NMR analysis.
Minimum 5 mg for 1H NMR analysis.
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Other Requirements:
Information on sample solubility.
Details of the specific NMR experiment(s) required (e.g., 1H, 13C, etc.).
COSHH (Control of Substances Hazardous to Health) data sheet for safe handling.
Contact us today to discuss your NMR spectroscopy needs and discover how our expertise can accelerate your research and development efforts.
Infra Red (IR) Spectroscopy
Infra Red (IR) Spectroscopy services provide accurate identification of pure compounds and the detection and identification of impurities. Using Fourier Transform Infrared (FT-IR) technology, we offer a powerful analytical solution for various chemical investigations.
The versatility of Attenuated Total Reflectance (ATR) allows for the analysis of a wide range of sample types, from liquids to hard solids, with minimal sample preparation. This makes our IR spectroscopy services highly efficient and accessible for diverse applications.
Key Applications of IR Spectroscopy
Compound Identification: Confirm the identity of known substances or identify unknown compounds.
Impurity Detection: Quickly pinpoint and characterise impurities within a sample.
Quality Control: Ensure product consistency and purity in manufacturing processes.
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Functional Group Analysis: Determine the presence or absence of specific chemical functional groups.
Key Applications of Optical Rotation
Our optical rotation services are indispensable for:
Characterization of Newly Synthesised Compounds: Confirm the enantiomeric purity and structural integrity of your novel chemical entities.
Quality Control of Pharmaceutical Substances: Ensure the enantiomeric purity of active pharmaceutical ingredients (APIs) and other drug components, critical for efficacy and safety.
Enantiomeric Purity Determination: Accurately assess the ratio of enantiomers in a sample, a key parameter in many chemical and pharmaceutical processes.
Sample Submission Requirements
To facilitate your IR analysis, please provide:
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Sample Requirements: Approximately 5mg of sample.
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Other Requirements: COSHH (Control of Substances Hazardous to Health) data for safe handling.
Contact us today to discuss your Infra-Red spectroscopy needs and how our FT-IR services can support your analytical goals.
Thermal Analysis Services
Thermal Analysis services investigate how the physical and chemical properties of a substance change with temperature or time under a controlled thermal program. This program can involve dynamic heating or cooling, isothermal holds, or a combination of these, providing comprehensive insights into material behaviour.
We offer a range of specialised thermal analysis techniques to meet your analytical needs:
Differential Scanning Calorimetry (DSC): Ideal for measuring heat flow related to transitions such as melting, crystallization, glass transitions, and curing. DSC analysis is crucial for understanding material stability and phase changes.
Thermo Gravimetric Analysis (TGA): Used to measure changes in sample weight as a function of temperature or time. TGA helps in determining decomposition temperatures, volatile content, moisture content, and composition of materials.
Sulphated Ash (Residue on Ignition - ROI): A technique for determining the inorganic content of a sample by burning off organic material and converting inorganic residues to sulphates.
Sample Submission Requirements
To ensure accurate and effective thermal analysis, please provide:
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Sample Requirements:
TGA: Minimum 25mg
DSC: Minimum 25mg
Sulphated Ash (ROI): Minimum 1g
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Other Requirements:
Desired experimental conditions (e.g., temperature range, heating rate, atmosphere).
COSHH (Control of Substances Hazardous to Health) data sheet for safe handling.
Contact us today to discuss your thermal analysis requirements and how our expertise can assist in characterising your materials.
Contact Exeter Analytical (UK) Ltd, in Coventry, today to discuss your requirements when it comes to Optical Rotation Analysis Services, and how our expertise can assist in characterising your materials.
024 7632 3223